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In phase 2 trials, retatrutide has been found to significantly lower levels of glycated hemoglobin (HbA1c)

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For the most severe forms of thalassemia, hematopoietic stem-cell transplantation (HSCT) is currently the only curative therapeutic option 2, 3 with busulfan (Bu) as the key component of the myeloablative regimen prior to HSCT